BME771

Bioconjugation chemistry is the science of coupling biomolecules for a wide range of applications. For example, proteins may be coupled with one polymer to enhance its stability in serum or polymers may be coupled to each other to form hydrogels. A wide variety of bioconjugates are used in the delivery of pharmaceuticals, in sensors, in medical diagnostics, and in tissue engineering. Basic concepts of chemical ligation, including the choice and design of conjugate linkers depending on the type of biomolecule and desired application, such as degradable versus nondegradable linkers. The class will focus on biomaterial and drug delivery strategies.

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